January 26, 2025
genxbio

An anti-perfringolysin O monoclonal antibody cross-reactive

An anti-perfringolysin O monoclonal antibody cross-reactive with streptolysin O protects towards streptococcal poisonous shock syndrome

Goal: Streptococcus pyogenes (Group A Streptococcus; GAS) causes quite a lot of infections that embrace life-threatening, extreme invasive GAS infections, similar to streptococcal poisonous shock syndrome (STSS), with > 30% mortality price, regardless of efficient antibiotics and remedy choices. STSS medical isolates extremely categorical streptolysin O (SLO), a member of a giant household of pore-forming toxins referred to as cholesterol-dependent cytolysins (CDCs). SLO is a crucial poisonous issue for GAS and could also be an efficient therapeutic goal for the remedy of STSS. Our purpose was to determine a monoclonal antibody (mAb) that reacts with SLO and has therapeutic potential for STSS remedy.
Outcomes: We centered on mAbs that had initially been established as neutralizing reagents to perfringolysin O (PFO), one other member of the CDC household, as some cross-reactivity with SLO had been reported. Right here, we confirmed cross-reactivity of an anti-PFO mAb named HS1 with SLO. In vitro evaluation revealed that HS1 mAb sufficiently prevented human neutrophils from being killed by STSS medical isolates. Moreover, prophylactic and therapeutic injection of HS1 mAb into C57BL/6 mice considerably improved the survival price following deadly an infection with an STSS medical isolate. These outcomes spotlight the therapeutic potential of HS1 mAb for STSS remedy.

GAPDH (HRP Conjugated)

MBS8528772-01mL 0.1mL
EUR 325

GAPDH (HRP Conjugated)

MBS8528772-5x01mL 5x0.1mL
EUR 1320

GAPDH (HRP conjugated)

MBS8534373-01mL 0.1mL
EUR 345

GAPDH (HRP conjugated)

MBS8534373-01mLAF405L 0.1mL(AF405L)
EUR 565

GAPDH (HRP conjugated)

MBS8534373-01mLAF405S 0.1mL(AF405S)
EUR 565

GAPDH (HRP conjugated)

MBS8534373-01mLAF610 0.1mL(AF610)
EUR 565

GAPDH (HRP conjugated)

MBS8534373-01mLAF635 0.1mL(AF635)
EUR 565

HRP Conjugated Avidin

BA1081-0.5 0.5ml
EUR 175.2

HRP Conjugated Avidin

BA1081-1 1ml
EUR 279.6

HRP Conjugated Avidin

MBS176682-05mL 0.5mL
EUR 190

HRP Conjugated Avidin

MBS176682-1mL 1mL
EUR 260

HRP Conjugated Avidin

MBS176682-5x1mL 5x1mL
EUR 1025

HRP Conjugated Stretavidin

BS10044 100ul
EUR 55
Description: WB ELISA IHC ICC

Streptavidin HRP Conjugated

LS1012 1.0 ml
EUR 95

HRP Conjugated Streptavidin

BA1088-0.5 0.5ml
EUR 175.2

HRP Conjugated Streptavidin

BA1088-1 1ml
EUR 279.6

Streptavidin HRP Conjugated

AS15-2860 1 mg
EUR 211

HRP Conjugated Streptavidin

MBS176633-05mL 0.5mL
EUR 190

HRP Conjugated Streptavidin

MBS176633-1mL 1mL
EUR 260

HRP Conjugated Streptavidin

MBS176633-5x1mL 5x1mL
EUR 1025

Streptavidin HRP Conjugated

MBS9458422-1mL 1mL
EUR 165

Streptavidin HRP Conjugated

MBS9458422-5x1mL 5x1mL
EUR 580

Streptavidin, HRP conjugated

S0900-001 1mg
EUR 360

HA-Tag(HRP Conjugated)

E11-12035 100ul
EUR 255
Description: Available in various conjugation types.

HA-Tag(HRP conjugated)

E8ET1703-12 100ul
EUR 275
Description: Available in various conjugation types.

HA-Tag (HRP Conjugated)

MBS8528768-01mL 0.1mL
EUR 325

HA-Tag (HRP Conjugated)

MBS8528768-5x01mL 5x0.1mL
EUR 1320

HA-Tag (HRP conjugated)

MBS8534415-01mL 0.1mL
EUR 345

HA-Tag (HRP conjugated)

MBS8534415-01mLAF405L 0.1mL(AF405L)
EUR 565

HA-Tag (HRP conjugated)

MBS8534415-01mLAF405S 0.1mL(AF405S)
EUR 565

HA-Tag (HRP conjugated)

MBS8534415-01mLAF610 0.1mL(AF610)
EUR 565

HA-Tag (HRP conjugated)

MBS8534415-01mLAF635 0.1mL(AF635)
EUR 565

GST-Tag(HRP Conjugated)

E11-12007-HRP 100ul
EUR 255
Description: Available in various conjugation types.

MBP-Tag(HRP Conjugated)

E11-12008-HRP 100ul
EUR 255
Description: Available in various conjugation types.

GFP-Tag(HRP Conjugated)

E11-12026-HRP 100ul
EUR 255
Description: Available in various conjugation types.

His-Tag(HRP Conjugated)

E11-12032 100ul
EUR 255
Description: Available in various conjugation types.

β-actin(HRP Conjugated)

E11-12056 100ul
EUR 255
Description: Available in various conjugation types.

GFP-Tag(HRP Conjugated)

E11-12152-HRP 100ul
EUR 255
Description: Available in various conjugation types.

GST-Tag(HRP conjugated)

E8ET1703-13 100ul
EUR 275
Description: Available in various conjugation types.

Myc-Tag HRP conjugated

E8M1405-5 200ul
EUR 275
Description: Available in various conjugation types.

GST-Tag (HRP Conjugated)

MBS8528764-01mL 0.1mL
EUR 325

GST-Tag (HRP Conjugated)

MBS8528764-5x01mL 5x0.1mL
EUR 1320

MBP-Tag (HRP Conjugated)

MBS8528765-01mL 0.1mL
EUR 325

MBP-Tag (HRP Conjugated)

MBS8528765-5x01mL 5x0.1mL
EUR 1320

GFP-Tag (HRP Conjugated)

MBS8528766-01mL 0.1mL
EUR 325

GFP-Tag (HRP Conjugated)

MBS8528766-5x01mL 5x0.1mL
EUR 1320

His-Tag (HRP Conjugated)

MBS8528767-01mL 0.1mL
EUR 325

His-Tag (HRP Conjugated)

MBS8528767-5x01mL 5x0.1mL
EUR 1320

GFP-Tag (HRP Conjugated)

MBS8528773-01mL 0.1mL
EUR 325

GFP-Tag (HRP Conjugated)

MBS8528773-5x01mL 5x0.1mL
EUR 1320

GST-Tag (HRP conjugated)

MBS8534416-01mL 0.1mL
EUR 345

GST-Tag (HRP conjugated)

MBS8534416-01mLAF405L 0.1mL(AF405L)
EUR 565

GST-Tag (HRP conjugated)

MBS8534416-01mLAF405S 0.1mL(AF405S)
EUR 565

GST-Tag (HRP conjugated)

MBS8534416-01mLAF610 0.1mL(AF610)
EUR 565

GST-Tag (HRP conjugated)

MBS8534416-01mLAF635 0.1mL(AF635)
EUR 565

Myc-Tag HRP conjugated

MBS8534576-01mLAF405L 0.1mL(AF405L)
EUR 565

Myc-Tag HRP conjugated

MBS8534576-01mLAF405S 0.1mL(AF405S)
EUR 565

Myc-Tag HRP conjugated

MBS8534576-01mLAF610 0.1mL(AF610)
EUR 565

Myc-Tag HRP conjugated

MBS8534576-01mLAF635 0.1mL(AF635)
EUR 565

Myc-Tag HRP conjugated

MBS8534576-02mL 0.2mL
EUR 345

HRP Conjugated Protein A

BA1080-0.5 0.5ml
EUR 224.4

HRP Conjugated Protein A

BA1080-1 1ml
EUR 400.8

HRP Conjugated Protein G

BA1083 0.5ml
EUR 135
Description: Western Blotting: 0.1-0.3μg/ml (ECL detection)_x000D_Western Blotting: 0.3-2μg/ml (DAB detection)_x000D_Immunohistochemistry (Paraffin-embedded Section): 5-10μg/ml_x000D_Immunohistochemistry (Frozen Section): 2-10μg/ml_x000D_ELISA: 0.025-0.05μg/ml_x000D_

beta Actin(HRP conjugated)

E8ET1702-67 100ul
EUR 275
Description: Available in various conjugation types.

beta Actin(HRP Conjugated)

E2382299 100ul
EUR 225
Description: Available in various conjugation types.

HRP Conjugated Protein A

MBS176613-05mL 0.5mL
EUR 225

HRP Conjugated Protein A

MBS176613-1mL 1mL
EUR 350

HRP Conjugated Protein A

MBS176613-5x1mL 5x1mL
EUR 1425

beta Actin (HRP conjugated)

MBS8534374-01mL 0.1mL
EUR 345

beta Actin (HRP conjugated)

MBS8534374-01mLAF405L 0.1mL(AF405L)
EUR 565

beta Actin (HRP conjugated)

MBS8534374-01mLAF405S 0.1mL(AF405S)
EUR 565

beta Actin (HRP conjugated)

MBS8534374-01mLAF610 0.1mL(AF610)
EUR 565

beta Actin (HRP conjugated)

MBS8534374-01mLAF635 0.1mL(AF635)
EUR 565

beta Actin (HRP Conjugated)

MBS8575631-01mL 0.1mL
EUR 305

beta Actin (HRP Conjugated)

MBS8575631-01mLAF405L 0.1mL(AF405L)
EUR 565

beta Actin (HRP Conjugated)

MBS8575631-01mLAF405S 0.1mL(AF405S)
EUR 565

beta Actin (HRP Conjugated)

MBS8575631-01mLAF610 0.1mL(AF610)
EUR 565

beta Actin (HRP Conjugated)

MBS8575631-01mLAF635 0.1mL(AF635)
EUR 565

F Antibody; HRP conjugated

MBS7004335-005mg 0.05mg
EUR 190

F Antibody; HRP conjugated

MBS7004335-01mg 0.1mg
EUR 270

F Antibody; HRP conjugated

MBS7004335-5x01mg 5x0.1mg
EUR 1205

GP Antibody; HRP conjugated

MBS7004433-005mg 0.05mg
EUR 190

GP Antibody; HRP conjugated

MBS7004433-01mg 0.1mg
EUR 270

GP Antibody; HRP conjugated

MBS7004433-5x01mg 5x0.1mg
EUR 1205

XG Antibody; HRP conjugated

MBS7004822-005mg 0.05mg
EUR 190

XG Antibody; HRP conjugated

MBS7004822-01mg 0.1mg
EUR 270

XG Antibody; HRP conjugated

MBS7004822-5x01mg 5x0.1mg
EUR 1205

E6 Antibody; HRP conjugated

MBS7005797-005mg 0.05mg
EUR 190

E6 Antibody; HRP conjugated

MBS7005797-01mg 0.1mg
EUR 270

E6 Antibody; HRP conjugated

MBS7005797-5x01mg 5x0.1mg
EUR 1205

AR Antibody, HRP conjugated

MBS7044982-005mg 0.05mg
EUR 190

AR Antibody, HRP conjugated

MBS7044982-01mg 0.1mg
EUR 270

AR Antibody, HRP conjugated

MBS7044982-5x01mg 5x0.1mg
EUR 1205

F5 Antibody, HRP conjugated

MBS7045449-005mg 0.05mg
EUR 190

F5 Antibody, HRP conjugated

MBS7045449-01mg 0.1mg
EUR 270

F5 Antibody, HRP conjugated

MBS7045449-5x01mg 5x0.1mg
EUR 1205

GK Antibody, HRP conjugated

MBS7045949-005mg 0.05mg
EUR 190

GK Antibody, HRP conjugated

MBS7045949-01mg 0.1mg
EUR 270

GK Antibody, HRP conjugated

MBS7045949-5x01mg 5x0.1mg
EUR 1205

C9 Antibody, HRP conjugated

MBS7046150-005mg 0.05mg
EUR 190

C9 Antibody, HRP conjugated

MBS7046150-01mg 0.1mg
EUR 270

C9 Antibody, HRP conjugated

MBS7046150-5x01mg 5x0.1mg
EUR 1205

C6 Antibody, HRP conjugated

MBS7047786-005mg 0.05mg
EUR 190

C6 Antibody, HRP conjugated

MBS7047786-01mg 0.1mg
EUR 270

C6 Antibody, HRP conjugated

MBS7047786-5x01mg 5x0.1mg
EUR 1205

PC Antibody, HRP conjugated

MBS7048831-005mg 0.05mg
EUR 190

PC Antibody, HRP conjugated

MBS7048831-01mg 0.1mg
EUR 270

PC Antibody, HRP conjugated

MBS7048831-5x01mg 5x0.1mg
EUR 1205

L1 Antibody, HRP conjugated

MBS7049528-005mg 0.05mg
EUR 190

L1 Antibody, HRP conjugated

MBS7049528-01mg 0.1mg
EUR 270

L1 Antibody, HRP conjugated

MBS7049528-5x01mg 5x0.1mg
EUR 1205

F9 Antibody, HRP conjugated

MBS7048146-005mg 0.05mg
EUR 190

F9 Antibody, HRP conjugated

MBS7048146-01mg 0.1mg
EUR 270

F9 Antibody, HRP conjugated

MBS7048146-5x01mg 5x0.1mg
EUR 1205

KL Antibody, HRP conjugated

MBS7049596-005mg 0.05mg
EUR 190

KL Antibody, HRP conjugated

MBS7049596-01mg 0.1mg
EUR 270

KL Antibody, HRP conjugated

MBS7049596-5x01mg 5x0.1mg
EUR 1205

GP Antibody, HRP conjugated

MBS7049784-005mg 0.05mg
EUR 190

GP Antibody, HRP conjugated

MBS7049784-01mg 0.1mg
EUR 270

GP Antibody, HRP conjugated

MBS7049784-5x01mg 5x0.1mg
EUR 1205

N Antibody, HRP conjugated

MBS7049808-005mg 0.05mg
EUR 190

N Antibody, HRP conjugated

MBS7049808-01mg 0.1mg
EUR 270

N Antibody, HRP conjugated

MBS7049808-5x01mg 5x0.1mg
EUR 1205

N Antibody, HRP conjugated

MBS7049856-005mg 0.05mg
EUR 190

N Antibody, HRP conjugated

MBS7049856-01mg 0.1mg
EUR 270

N Antibody, HRP conjugated

MBS7049856-5x01mg 5x0.1mg
EUR 1205

gB Antibody, HRP conjugated

MBS7049952-005mg 0.05mg
EUR 190

gB Antibody, HRP conjugated

MBS7049952-01mg 0.1mg
EUR 270

gB Antibody, HRP conjugated

MBS7049952-5x01mg 5x0.1mg
EUR 1205

AK Antibody, HRP conjugated

MBS7049996-005mg 0.05mg
EUR 190

AK Antibody, HRP conjugated

MBS7049996-01mg 0.1mg
EUR 270

AK Antibody, HRP conjugated

MBS7049996-5x01mg 5x0.1mg
EUR 1205

HA Antibody, HRP conjugated

MBS7050052-005mg 0.05mg
EUR 190

HA Antibody, HRP conjugated

MBS7050052-01mg 0.1mg
EUR 270

HA Antibody, HRP conjugated

MBS7050052-5x01mg 5x0.1mg
EUR 1205

NP Antibody, HRP conjugated

MBS7053102-005mg 0.05mg
EUR 190

NP Antibody, HRP conjugated

MBS7053102-01mg 0.1mg
EUR 270

NP Antibody, HRP conjugated

MBS7053102-5x01mg 5x0.1mg
EUR 1205

B1 Antibody, HRP conjugated

MBS7053310-005mg 0.05mg
EUR 190

B1 Antibody, HRP conjugated

MBS7053310-01mg 0.1mg
EUR 270

B1 Antibody, HRP conjugated

MBS7053310-5x01mg 5x0.1mg
EUR 1205

X Antibody, HRP conjugated

MBS7051181-005mg 0.05mg
EUR 190

X Antibody, HRP conjugated

MBS7051181-01mg 0.1mg
EUR 270

X Antibody, HRP conjugated

MBS7051181-5x01mg 5x0.1mg
EUR 1205

TH Antibody, HRP conjugated

MBS7052442-005mg 0.05mg
EUR 190

TH Antibody, HRP conjugated

MBS7052442-01mg 0.1mg
EUR 270

TH Antibody, HRP conjugated

MBS7052442-5x01mg 5x0.1mg
EUR 1205

N Antibody, HRP conjugated

MBS7052614-005mg 0.05mg
EUR 190

N Antibody, HRP conjugated

MBS7052614-01mg 0.1mg
EUR 270

N Antibody, HRP conjugated

MBS7052614-5x01mg 5x0.1mg
EUR 1205

C3 Antibody, HRP conjugated

MBS7052710-005mg 0.05mg
EUR 190

C3 Antibody, HRP conjugated

MBS7052710-01mg 0.1mg
EUR 270

C3 Antibody, HRP conjugated

MBS7052710-5x01mg 5x0.1mg
EUR 1205

S Antibody, HRP conjugated

MBS7136231-005mL 0.05mL
EUR 190

S Antibody, HRP conjugated

MBS7136231-01mL 0.1mL
EUR 270

S Antibody, HRP conjugated

MBS7136231-5x01mL 5x0.1mL
EUR 1205

S Antibody, HRP conjugated

MBS7136232-005mL 0.05mL
EUR 190

S Antibody, HRP conjugated

MBS7136232-01mL 0.1mL
EUR 270

S Antibody, HRP conjugated

MBS7136232-5x01mL 5x0.1mL
EUR 1205

N Antibody, HRP conjugated

MBS7136238-005mL 0.05mL
EUR 190

N Antibody, HRP conjugated

MBS7136238-01mL 0.1mL
EUR 270

N Antibody, HRP conjugated

MBS7136238-5x01mL 5x0.1mL
EUR 1205

N Antibody, HRP Conjugated

MBS7134748-005mL 0.05mL
EUR 190

N Antibody, HRP Conjugated

MBS7134748-01mL 0.1mL
EUR 270

N Antibody, HRP Conjugated

MBS7134748-5x01mL 5x0.1mL
EUR 1205

M Antibody, HRP Conjugated

MBS7134752-005mL 0.05mL
EUR 190

M Antibody, HRP Conjugated

MBS7134752-01mL 0.1mL
EUR 270

M Antibody, HRP Conjugated

MBS7134752-5x01mL 5x0.1mL
EUR 1205

Tf Antibody, HRP Conjugated

MBS7134855-005mL 0.05mL
EUR 190

Tf Antibody, HRP Conjugated

MBS7134855-01mL 0.1mL
EUR 270

Tf Antibody, HRP Conjugated

MBS7134855-5x01mL 5x0.1mL
EUR 1205

TH Antibody, HRP Conjugated

MBS7113619-005mg 0.05mg
EUR 190

TH Antibody, HRP Conjugated

MBS7113619-01mg 0.1mg
EUR 270

TH Antibody, HRP Conjugated

MBS7113619-5x01mg 5x0.1mg
EUR 1205

S Antibody, HRP Conjugated

MBS7113727-005mL 0.05mL
EUR 190

S Antibody, HRP Conjugated

MBS7113727-01mL 0.1mL
EUR 270

Discovery and Practical Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody

Background: As a consequence of the invention of an extracellular part chargeable for the development of tau pathology, tau immunotherapy is being extensively explored in each preclinical and medical research as a illness modifying technique for the remedy of Alzheimer’s illness.
Goal: Describe the traits of the anti-phospho (T212/T217) tau selective antibody PT3 and its humanized variant hPT3.
Strategies: By performing completely different immunization campaigns, a big assortment of antibodies has been generated and prioritized. In depth, in vitro characterization utilizing floor plasmon resonance, phospho-epitope mapping, and X-ray crystallography experiments have been carried out. Additional characterization concerned immunohistochemical staining on mouse- and human postmortem tissue and neutralization of tau seeding by immunodepletion assays.
Outcomes and conclusion: Varied in vitro experiments demonstrated a excessive intrinsic affinity for PT3 and hPT3 for AD brain-derived paired helical filaments but additionally to non-aggregated phospho (T212/T217) tau. Additional useful analyses in mobile and in vivo fashions of tau seeding demonstrated virtually full depletion of tau seeds in an AD mind homogenate. Ongoing trials will present the medical analysis of the tau spreading speculation in Alzheimer’s illness.

[Preparation of highly sensitive monoclonal antibody against aflatoxin B_1 and its application in rapid detection of contamination in Ziziphi Spinosae Semen]

  • A extremely delicate monoclonal antibody towards aflatoxin B_1(AFB_1) was ready and an oblique competitors enzyme-linked immunosorbent assay(ic-ELISA) was established primarily based on the antibody which was used for high-throughput and fast screening of AFB_1 contamination in Chinese language natural medicines to make sure the protection of medicine.
  • On this examine, the construction of AFB_1 was modified by improved oxime methodology, and the provider protein was coupled by EDC-NHS methodology to acquire the whole antigen of AFB_1, which was extra handy and environmental pleasant. The Balb/c feminine mice have been immunized utilizing rising the immunization dose and varied methods of injection, and eventually the AFB_1 monoclonal antibody was ready.
  • The AFB_1 monoclonal antibody belongs to IgG_(2 b) immunoglobulin by figuring out its immunological traits, and its sensitivity(IC_(50)) can attain 0.15 μg·L~(-1), and the affi-nity is 2.81×10~Eight L·mol~(-1). The cross-reaction charges of AFB_2, AFG_1, and AFG_2 have been 35.07%, 8.75%, and 1.15%, respectively, and there was virtually no cross-reactivity with different mycotoxins. Based mostly on the excessive sensitivity and specificity of the antibody, an ic-ELISA methodology was established and utilized to the willpower of AFB_1 contamination in Ziziphi Spinosae Semen.
  • In response to the matrix matching customary curve, the linear focus vary for AFB_1 was 0.05-0.58 μg·L~(-1)(R~2=0.992), the recoveries have been 88.00%-119.0%, and the detection restrict was 1.69 μg·kg~(-1). The AFB_1 in 33 batches of Ziziphi Spinosae Semen samples was decided by ic-ELISA, and the contamination stage was 3.62-206.58 μg·kg~(-1). The linear correlation coefficient between the detection outcomes of ic-ELISA and UHPLC-MS/MS was 0.996, and there have been no false constructive and false adverse instances.
  • It signifies that the established ic-ELISA is correct and dependable, and will present a easy and efficient method for quick screening of AFB_1 contamination in Ziziphi Spinosae Semen, and likewise might be thought-about because the reference for the detection and monitoring of AFB_1 contamination in different Chinese language natural medicines.

Polyclonal AntibodyPC1 Polyclonal Antibody

RD81942A-200uL 200μL
EUR 630
Description: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Polyclonal AntibodyPC1 Polyclonal Antibody

RD81942A-60uL 60μL
EUR 204
Description: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Polyclonal AntibodyPC4 Polyclonal Antibody

RD83593A-120uL 120μL
EUR 360
Description: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Polyclonal AntibodyPC4 Polyclonal Antibody

RD83593A-200uL 200μL
EUR 630
Description: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Polyclonal AntibodyPC4 Polyclonal Antibody

RD83593A-60uL 60μL
EUR 204
Description: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Polyclonal ETO polyclonal antibody

APR00372G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal SHH Polyclonal Antibody

APR00434G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SHH Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ETO polyclonal antibody

APR00435G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal p53 polyclonal antibody

APR00443G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal G9a polyclonal antibody

APR00448G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human G9a polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal YY1 polyclonal antibody

APR14018G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human YY1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PML polyclonal antibody

AMR09397G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PML polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal AntibodyP1 Rabbit Polyclonal Antibody

ES11752-100ul 100ul
EUR 124
Description: WB, ELISA

Polyclonal AntibodyP1 Rabbit Polyclonal Antibody

ES11752-50ul 50ul
EUR 74
Description: WB, ELISA

Polyclonal AntibodyP3 Rabbit Polyclonal Antibody

ES6454-100ul 100ul
EUR 124
Description: WB, IHC, ELISA

Polyclonal AntibodyP3 Rabbit Polyclonal Antibody

ES6454-50ul 50ul
EUR 74
Description: WB, IHC, ELISA

Polyclonal AntibodyP5 Rabbit Polyclonal Antibody

ES4829-100ul 100ul
EUR 124
Description: WB, IHC, ELISA

Polyclonal AntibodyP5 Rabbit Polyclonal Antibody

ES4829-50ul 50ul
EUR 74
Description: WB, IHC, ELISA

Polyclonal AntibodyP2 Rabbit Polyclonal Antibody

ES10016-100ul 100ul
EUR 124
Description: WB, ELISA

Polyclonal AntibodyP2 Rabbit Polyclonal Antibody

ES10016-50ul 50ul
EUR 74
Description: WB, ELISA

Polyclonal AntibodyP4 Rabbit Polyclonal Antibody

ES10017-100ul 100ul
EUR 124
Description: WB, ELISA

Polyclonal AntibodyP4 Rabbit Polyclonal Antibody

ES10017-50ul 50ul
EUR 74
Description: WB, ELISA

Polyclonal RARA polyclonal antibody

APR00370G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EzH2 polyclonal antibody

APR00373G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EzH2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BRD2 polyclonal antibody

APR00374G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BMI1 polyclonal antibody

APR00376G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EZH2 polyclonal antibody

APR00436G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal RARA polyclonal antibody

APR00437G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EZH2 polyclonal antibody

APR00439G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal CHD4 polyclonal antibody

APR00444G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BRD2 polyclonal antibody

APR00447G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Hira polyclonal antibody

APR00449G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Hira polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal SPI1 polyclonal antibody

APR00451G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SPI1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BMI1 polyclonal antibody

APR00457G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal CHD4 polyclonal antibody

APR00459G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Rtf1 polyclonal antibody

APR11187G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Rtf1 polyclonal antibody

APR11188G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal SOX4 polyclonal antibody

APR13475G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SOX4 polyclonal . This antibody is tested and proven to work in the following applications:

Rabbit Polyclonal Antibody PC1 Rabbit Polyclonal Antibody

MBS9465163-005mL 0.05mL
EUR 300

Rabbit Polyclonal Antibody PC1 Rabbit Polyclonal Antibody

MBS9465163-01mL 0.1mL
EUR 390

Rabbit Polyclonal Antibody PC1 Rabbit Polyclonal Antibody

MBS9465163-5x01mL 5x0.1mL
EUR 1610

Rabbit Polyclonal Antibody PC4 Rabbit Polyclonal Antibody

MBS9465999-005mL 0.05mL
EUR 300

Rabbit Polyclonal Antibody PC4 Rabbit Polyclonal Antibody

MBS9465999-01mL 0.1mL
EUR 390

Rabbit Polyclonal Antibody PC4 Rabbit Polyclonal Antibody

MBS9465999-5x01mL 5x0.1mL
EUR 1610

Polyclonal PADI4 polyclonal antibody

APR08916G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PADI4 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MYH11 polyclonal antibody

APR00438G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MYH11 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal CIITA polyclonal antibody

APR00442G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CIITA polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal HDAC1 polyclonal antibody

APR00445G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Spt16 polyclonal antibody

APR00446G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal BCL7C polyclonal antibody

APR00452G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BCL7C polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal LRWD1 polyclonal antibody

APR00455G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LRWD1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal KDM4D polyclonal antibody

APR00458G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human KDM4D polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Spt16 polyclonal antibody

APR00460G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Med26 polyclonal antibody

APR12517G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Med26 polyclonal antibody

APR12518G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody

APR12525G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody

APR12526G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody

APR12527G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody

AMM06350G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal MeCP2 polyclonal antibody

AMM06351G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PPARG polyclonal antibody

AMR09459G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PPARG polyclonal antibody

AMR09486G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ZMYND8 polyclonal antibody

AMM08559G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZMYND8 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal FKBP51 polyclonal antibody

APR15992G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FKBP51 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal PIWIL2 polyclonal antibody

APR17846G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PIWIL2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JMJD2c polyclonal antibody

APR00375G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JMJD2c polyclonal antibody

APR00450G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal LYDG10 polyclonal antibody

APR00456G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LYDG10 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JARID2 polyclonal antibody

APR12450G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal ACTL6B polyclonal antibody

AMM05547G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTL6B polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal JARID2 polyclonal antibody

AMM06027G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal AKR1B10 Polyclonal Antibody

APG01659G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AKR1B10 Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal p53K372me1 polyclonal antibody

APR00440G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53K372me1 polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal FGF-1 Polyclonal Antibody

APR00423G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FGF-1 Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal RFX-AP polyclonal antibody

APR00441G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RFX-AP polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal EIF2C1/2 polyclonal antibody

APR00453G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EIF2C1/2 polyclonal . This antibody is tested and proven to work in the following applications:

Rabbit Polyclonal AntibodyPC1 Rabbit Polyclonal Antibody

53940 100ul
EUR 439

Rabbit Polyclonal AntibodyPC4 Rabbit Polyclonal Antibody

54946 100ul
EUR 439

Polyclonal TGF-beta3 Polyclonal Antibody

APG00008G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human TGF-beta3 Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal sRANK Ligand Polyclonal Antibody

APR00294G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human sRANK Ligand Polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Smc3K112/113ac polyclonal antibody

APR00454G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Smc3K112/113ac polyclonal . This antibody is tested and proven to work in the following applications:

Polyclonal Runx1/AML1-ETO polyclonal antibody

APR00371G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Runx1/AML1-ETO polyclonal . This antibody is tested and proven to work in the following applications:

42982 Polyclonal Antibody

MBS2547600-006mL 0.06mL
EUR 190

42982 Polyclonal Antibody

MBS2547600-012mL 0.12mL
EUR 265

42982 Polyclonal Antibody

MBS2547600-02mL 0.2mL
EUR 415

42982 Polyclonal Antibody

MBS2547600-5x02mL 5x0.2mL
EUR 1835

42803 Polyclonal Antibody

MBS2547745-006mL 0.06mL
EUR 180

42803 Polyclonal Antibody

MBS2547745-012mL 0.12mL
EUR 260

42803 Polyclonal Antibody

MBS2547745-02mL 0.2mL
EUR 405

42803 Polyclonal Antibody

MBS2547745-5x02mL 5x0.2mL
EUR 1725

42987 Polyclonal Antibody

MBS2548299-006mL 0.06mL
EUR 190

42987 Polyclonal Antibody

MBS2548299-012mL 0.12mL
EUR 265

42987 Polyclonal Antibody

MBS2548299-02mL 0.2mL
EUR 415

42987 Polyclonal Antibody

MBS2548299-5x02mL 5x0.2mL
EUR 1835

Rabbit polyclonal anti-IL-19 Polyclonal antibody

TA319096 100 µg Ask for price

Polyclonal antibody-Leptin antibody

PA-RA-07883 100ug
EUR 400

HO Polyclonal Antibody

27513 100ul
EUR 439

PD Polyclonal Antibody

27584 100ul
EUR 439

HR Polyclonal Antibody

27586 100ul
EUR 439

HR Polyclonal Antibody

27586-100ul 100ul
EUR 302.4

HR Polyclonal Antibody

27586-50ul 50ul
EUR 224.4

HR Polyclonal Antibody

27636 100ul
EUR 439

HR Polyclonal Antibody

27636-100ul 100ul
EUR 302.4

HR Polyclonal Antibody

27636-50ul 50ul
EUR 224.4

C6 Polyclonal Antibody

27318-100ul 100ul
EUR 302.4

C6 Polyclonal Antibody

27318-50ul 50ul
EUR 224.4

C2 Polyclonal Antibody

27320-100ul 100ul
EUR 302.4

C2 Polyclonal Antibody

27320-50ul 50ul
EUR 224.4

C5 Polyclonal Antibody

31439-100ul 100ul
EUR 302.4

C5 Polyclonal Antibody

31439-50ul 50ul
EUR 224.4

L1 Polyclonal Antibody

42503 100μg
EUR 390

L1 Polyclonal Antibody

42503-100ul 100ul
EUR 399.6

AP Polyclonal Antibody

40598 100ul
EUR 319

AR Polyclonal Antibody

40609 100ul
EUR 319

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