Modeling the Impact of Amino Acids and Copper on Monoclonal Antibody Productiveness and Glycosylation: A Modular Strategy
- In manufacturing monoclonal antibodies (mAbs), it’s essential to have the ability to predict how course of situations and dietary supplements have an effect on antibody productiveness and high quality attributes, particularly glycosylation. Supplemental inputs, corresponding to amino acids and hint metals within the media, have been reported to have an effect on cell metabolism and glycosylation; understanding and quantifying their results are important for efficient course of improvement.
- Our goal is to current and validate, by way of a commercially related cell tradition course of, a method for capturing such results quantitatively and effectively in a mannequin. Whereas at present out there fashions can predict mAb manufacturing or glycosylation dynamics precisely beneath particular course of configurations, adapting them to new processes stays difficult, as a result of it includes modifying all the mannequin construction and sometimes requires some mechanistic understanding of how cells behave beneath new situations.
- Right here, we current a modular modeling method for adapting an current mannequin for a fed-batch Chinese language hamster ovary (CHO) cell tradition course of with out structural modifications or mechanistic perception. As an alternative, we use information, obtained from designed experimental perturbations in media concentrations of asparagine, glutamate, and copper, to coach and validate a supplemental enter impact mannequin, which approximates residual course of dynamics when supplemental inputs deviate from the baseline, and which is used to “patch” the prevailing mannequin.
- The mixed mannequin can be utilized for process-specific, model-based course of improvement to enhance productiveness and to fulfill product high quality targets extra effectively. Our mannequin was developed for a selected CHO cell line; nonetheless, the modeling methodology and evaluation are usually relevant to different cell traces and cell varieties. This text is protected by copyright. All rights reserved.
ProtoGlow ECL 200ml Kit |
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NAT1010 | National Diagnostics | EACH | EUR 354 |
ProtoGlow ECL 500ml Kit |
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NAT1012 | National Diagnostics | EACH | EUR 627.6 |
100G Acrylamide |
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NAT1014 | National Diagnostics | 100G | EUR 120 |
500G Acrylamide |
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NAT1016 | National Diagnostics | 500G | EUR 261.6 |
1KG Acrylamide |
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NAT1018 | National Diagnostics | 1KG | EUR 412.8 |
25G AquaPor LE |
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NAT1020 | National Diagnostics | 25G | EUR 132 |
100G AquaPor LE GTAC |
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NAT1022 | National Diagnostics | 100G | EUR 250.8 |
500G AquaPor LE GTAC |
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NAT1024 | National Diagnostics | 500G | EUR 878.4 |
25G AquaPor ES |
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NAT1026 | National Diagnostics | 25G | EUR 152.4 |
100G AquaPor ES |
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NAT1028 | National Diagnostics | 100G | EUR 350.4 |
25G AquaPor LM |
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NAT1030 | National Diagnostics | 25G | EUR 288 |
100G AquaPor LM |
|||
NAT1032 | National Diagnostics | 100G | EUR 860.4 |
25G AquaPor HR |
|||
NAT1034 | National Diagnostics | 25G | EUR 236.4 |
100G AquaPor HR |
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NAT1036 | National Diagnostics | 100G | EUR 592.8 |
25G AquaPor 3:1 |
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NAT1038 | National Diagnostics | 25G | EUR 250.8 |
100G AquaPor 3:1 |
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NAT1040 | National Diagnostics | 100G | EUR 570 |
25G Bis (Methylene Bis-Acrylamide) |
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NAT1042 | National Diagnostics | 25G | EUR 100.8 |
25G DATD Ultrapure |
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NAT1044 | National Diagnostics | 25G | EUR 168 |
250G Glycine |
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NAT1046 | National Diagnostics | 250G | EUR 94.8 |
1KG Glycine Ultrapure |
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NAT1048 | National Diagnostics | 1KG | EUR 128.4 |
250G Tris |
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NAT1050 | National Diagnostics | 250G | EUR 102 |
1KG Tris Ultrapure |
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NAT1052 | National Diagnostics | 1KG | EUR 177.6 |
100G Tricine |
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NAT1054 | National Diagnostics | 100G | EUR 120 |
100G Ion Exchange Resin (mixed bed) |
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NAT1056 | National Diagnostics | 100G | EUR 96 |
25G Riboflavin |
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NAT1058 | National Diagnostics | 25G | EUR 96 |
25ML TEMED |
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NAT1060 | National Diagnostics | 25ML | EUR 99.6 |
25G Ammonium Persulfate |
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NAT1062 | National Diagnostics | 25G | EUR 96 |
100G Ammonium Persulfate |
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NAT1064 | National Diagnostics | 100G | EUR 118.8 |
1G Dithiothreitol (DTT) |
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NAT1066 | National Diagnostics | 1G | EUR 103.2 |
5G Dithiothreitol (DTT) |
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NAT1068 | National Diagnostics | 5G | EUR 183.6 |
50ML 2-Mercaptoethanol |
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NAT1070 | National Diagnostics | 50ML | EUR 112.8 |
100G SDS Ultrapure |
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NAT1072 | National Diagnostics | 100G | EUR 111.6 |
1KG SDS Ultrapure |
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NAT1074 | National Diagnostics | 1KG | EUR 457.2 |
250G Urea |
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NAT1076 | National Diagnostics | 250G | EUR 98.4 |
1KG Urea |
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NAT1078 | National Diagnostics | 1KG | EUR 138 |
450ML Glycerol Ultrapure |
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NAT1080 | National Diagnostics | 450ML | EUR 132 |
200ML Tween 20 Ultrapure |
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NAT1082 | National Diagnostics | 200ML | EUR 132 |
1L Tween 20 |
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NAT1084 | National Diagnostics | 1L | EUR 169.2 |
200ML Formamide |
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NAT1086 | National Diagnostics | 200ML | EUR 111.6 |
500ML Boric Acid |
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NAT1088 | National Diagnostics | 500ML | EUR 103.2 |
100G EDTA |
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NAT1090 | National Diagnostics | 100G | EUR 94.8 |
500G EDTA |
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NAT1092 | National Diagnostics | 500G | EUR 177.6 |
GelDry Film 11 X 12 cm |
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NAT1094 | National Diagnostics | PK50 | EUR 100.8 |
25ML Formamide CE |
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NAT1096 | National Diagnostics | 25ML | Ask for price |
25ML Glass Bond |
|||
NAT1098 | National Diagnostics | 25ML | EUR 158.4 |
450ML Glass Free |
|||
NAT1100 | National Diagnostics | 450ML | EUR 196.8 |
GelDry Film 22.5 X 22.5 cm |
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NAT1102 | National Diagnostics | PK50 | EUR 130.8 |
1L DEPC Treated Water |
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NAT1104 | National Diagnostics | 1L | EUR 120 |
Sterling Rapid Silver Stain Kit |
|||
NAT1106 | National Diagnostics | 1KIT | EUR 265.2 |
1L ProtoBlue Safe |
|||
NAT1108 | National Diagnostics | 1L | EUR 159.6 |
4L ProtoBlue Safe |
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NAT1110 | National Diagnostics | 4L | EUR 282 |
1L ProtoStain Blue |
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NAT1112 | National Diagnostics | 1L | EUR 164.4 |
25ML Nuclistain |
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NAT1114 | National Diagnostics | 25ML | EUR 128.4 |
450ML AcrylaGel 30% |
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NAT1116 | National Diagnostics | 450ML | EUR 128.4 |
1L AcrylaGel 30% |
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NAT1118 | National Diagnostics | 1L | EUR 177.6 |
450ML Bis-AcrylaGel 2% |
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NAT1120 | National Diagnostics | 450ML | EUR 98.4 |
1L Bis-AcrylaGel 2% |
|||
NAT1122 | National Diagnostics | 1L | EUR 111.6 |
450ML UreaGel 29:1 Concentrate |
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NAT1124 | National Diagnostics | 450ML | EUR 133.2 |
1L UreaGel 29:1 Concentrate |
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NAT1126 | National Diagnostics | 1L | EUR 183.6 |
UreaGel 29:1 System 1L Kit |
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NAT1128 | National Diagnostics | EACH | EUR 171.6 |
UreaGel 29:1 System 2.2L Kit |
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NAT1130 | National Diagnostics | EACH | EUR 253.2 |
450ML SequaGel UreaGel Concentrate |
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NAT1132 | National Diagnostics | 450ML | EUR 126 |
1L SequaGel UreaGel Concentrate |
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NAT1134 | National Diagnostics | 1L | EUR 160.8 |
SequaGel Sequencing System 1L Kit |
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NAT1136 | National Diagnostics | 1KIT | EUR 171.6 |
SequaGel Sequencing System 2.2L Kit |
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NAT1138 | National Diagnostics | EACH | EUR 253.2 |
100ML SequaGel Buffer |
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NAT1140 | National Diagnostics | 100ML | EUR 80.4 |
200ML SequaGel UreaGel Buffer |
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NAT1142 | National Diagnostics | 200ML | EUR 84 |
450ML SequaGel UreaGel-6 |
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NAT1144 | National Diagnostics | 450ML | EUR 115.2 |
1L SequaGel UreaGel-6 |
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NAT1146 | National Diagnostics | 1L | EUR 151.2 |
450ML SequaGel UreaGel-8 |
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NAT1148 | National Diagnostics | 450ML | EUR 115.2 |
1L SequaGel UreaGel-8 |
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NAT1150 | National Diagnostics | 1L | EUR 151.2 |
450ML SequaGel UreaGel Diluent |
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NAT1152 | National Diagnostics | 450ML | EUR 90 |
1L SequaGel UreaGel Diluent |
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NAT1154 | National Diagnostics | 1L | EUR 103.2 |
90ML SequaGel Complete Buffer |
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NAT1156 | National Diagnostics | 90ML | EUR 79.2 |
200ML SequaGel UreaGel Complete Buffer |
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NAT1158 | National Diagnostics | 200ML | EUR 85.2 |
450ML SequaGel XR |
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NAT1160 | National Diagnostics | 450ML | EUR 126 |
1L SequaGel XR |
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NAT1162 | National Diagnostics | 1L | EUR 165.6 |
100ML SequaGel XR Concentrate |
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NAT1164 | National Diagnostics | 100ML | EUR 128.4 |
450ML SequaGel XR Concentrate |
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NAT1166 | National Diagnostics | 450ML | EUR 361.2 |
200ML SequaGel MD Monomer Solution |
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NAT1168 | National Diagnostics | 200ML | EUR 220.8 |
SequaGel MD SSCP Kit |
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NAT1170 | National Diagnostics | 1KIT | EUR 253.2 |
SequaGel MD Heteroduplex Kit |
|||
NAT1172 | National Diagnostics | EACH | EUR 265.2 |
1.2ML SequaGel MD SSCP Stop Solution |
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NAT1174 | National Diagnostics | 1.2ML | EUR 85.2 |
450ML AccuGel 19:1 (30%) |
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NAT1176 | National Diagnostics | 450ML | EUR 126 |
1L AccuGel 19:1 (30%) |
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NAT1178 | National Diagnostics | 1L | EUR 165.6 |
450ML AccuGel 19:1 (40%) |
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NAT1180 | National Diagnostics | 450ML | EUR 130.8 |
1L AccuGel 19:1 (40%) |
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NAT1182 | National Diagnostics | 1L | EUR 168 |
450ML AccuGel 29:1 (30%) |
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NAT1184 | National Diagnostics | 450ML | EUR 126 |
1L AccuGel 29:1 (30%) |
|||
NAT1186 | National Diagnostics | 1L | EUR 165.6 |
450ML AccuGel 29:1 (40%) |
|||
NAT1188 | National Diagnostics | 450ML | EUR 130.8 |
1L AccuGel 29:1 (40%) |
|||
NAT1190 | National Diagnostics | 1L | EUR 168 |
1.2ML Triple Dye Loading Buffer (6X) |
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NAT1192 | National Diagnostics | 1.2ML | EUR 85.2 |
UreaGel Loading Buffer |
|||
NAT1194 | National Diagnostics | 10X1ML | EUR 222 |
1L TBE 10X |
|||
NAT1196 | National Diagnostics | 1L | EUR 98.4 |
4L TBE 10X |
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NAT1198 | National Diagnostics | 4L | EUR 145.2 |
1L TBE 5X |
|||
NAT1200 | National Diagnostics | 1L | EUR 92.4 |
4L TBE 5X |
|||
NAT1202 | National Diagnostics | 4L | EUR 111.6 |
25ML TE BUFFER 100X |
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NAT1204 | National Diagnostics | 25ML | EUR 98.4 |
25ML 10X CE Buffer |
|||
NAT1206 | National Diagnostics | 25ML | EUR 138 |
100ML 10X CE Buffer |
|||
NAT1208 | National Diagnostics | 100ML | EUR 196.8 |
450ML 20X Tris-MOPS SDS |
|||
NAT1210 | National Diagnostics | 450ML | EUR 130.8 |
450ML 20X Tris-MEPS SDS |
|||
NAT1212 | National Diagnostics | 450ML | EUR 130.8 |
1L Tris-Tricine-SDS PAGE Buffer (10X) |
|||
NAT1214 | National Diagnostics | 1L | EUR 217.2 |
1L Tris-Glycine-SDS PAGE Buffer (10X) |
|||
NAT1216 | National Diagnostics | 1L | EUR 105.6 |
4L Tris-Glycine-SDS PAGE Buffer (10X) |
|||
NAT1218 | National Diagnostics | 4L | EUR 148.8 |
1L TTE Glycerol Tolerant Buffer 20X |
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NAT1220 | National Diagnostics | 1L | EUR 160.8 |
1L TAE Buffer 50X |
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NAT1222 | National Diagnostics | 1L | EUR 148.8 |
1L SSC Buffer 20X |
|||
NAT1224 | National Diagnostics | 1L | EUR 98.4 |
4L SSC Buffer 20X |
|||
NAT1226 | National Diagnostics | 4L | EUR 174 |
100ML SDS Solution 20% |
|||
NAT1228 | National Diagnostics | 100ML | EUR 92.4 |
450ML SDS Solution 20% |
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NAT1230 | National Diagnostics | 450ML | EUR 138 |
1L Denaturation Solution |
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NAT1232 | National Diagnostics | 1L | EUR 102 |
1L Neutralization Solution |
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NAT1234 | National Diagnostics | 1L | EUR 102 |
50G Dextran Sulfate |
|||
NAT1236 | National Diagnostics | 50G | EUR 193.2 |
250G Dextran Sulfate |
|||
NAT1238 | National Diagnostics | 250G | EUR 524.4 |
1L Tris-Glycine Electroblotting Buffer 10X |
|||
NAT1240 | National Diagnostics | 1L | EUR 102 |
4L Tris-Glycine Electroblotting Buffer 10X |
|||
NAT1242 | National Diagnostics | 4L | EUR 145.2 |
1L TBS (10X) Tris Buffered Saline |
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NAT1244 | National Diagnostics | 1L | EUR 126 |
1L TBST (10X) Tris Buffered Saline w/Tween 20 |
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NAT1246 | National Diagnostics | 1L | EUR 126 |
ProtoGel Sample Prep Kit |
|||
NAT1248 | National Diagnostics | EACH | EUR 223.2 |
Protein Loading Buffer Blue 2X |
|||
NAT1250 | National Diagnostics | 10X1ML | EUR 105.6 |
Protein Loading Buffer 5X |
|||
NAT1252 | National Diagnostics | 10X1ML | EUR 151.2 |
50ML Protein Precipitation Kit |
|||
NAT1254 | National Diagnostics | 50ML | EUR 270 |
100ML ProtoLift Western Strip Buffer |
|||
NAT1256 | National Diagnostics | 100ML | EUR 121.2 |
450ML ProtoGel (30%) |
|||
NAT1258 | National Diagnostics | 450ML | EUR 136.8 |
1L ProtoGel (30%) |
|||
NAT1260 | National Diagnostics | 1L | EUR 187.2 |
450ML ProtoGel (40%) |
|||
NAT1262 | National Diagnostics | 450ML | EUR 157.2 |
1L ProtoGel (40%) |
|||
NAT1264 | National Diagnostics | 1L | EUR 204 |
450ML ProtoGel Resolving Buffer 4X |
|||
NAT1266 | National Diagnostics | 450ML | EUR 100.8 |
1L ProtoGel Resolving Buffer |
|||
NAT1268 | National Diagnostics | 1L | EUR 128.4 |
200ML ProtoGel Stacking Buffer |
|||
NAT1270 | National Diagnostics | 200ML | EUR 92.4 |
100ML ProtoGel Quick-Cast 12% |
|||
NAT1272 | National Diagnostics | 100ML | EUR 105.6 |
450ML ProtoGel Quick-Cast 12% |
|||
NAT1274 | National Diagnostics | 450ML | EUR 223.2 |
Biased anti-idiotype response in rabbits results in high-affinity monoclonal antibodies to biologics
Antibody formation to human(ized) therapeutic antibodies in people is extremely skewed towards anti-idiotype responses, in all probability as a result of the idiotype is the one ‘international’ a part of the antibody molecule. Right here, we analyzed antibody responses to F(ab’)2 fragments of a panel of 17 human(ized) therapeutic antibodies in rabbits. Homology between the rabbit germline and the human(ized) antibodies is average not just for the variable domains (each the complementarity-determining regions and the framework areas), but in addition for the fixed domains (66% or much less).
However, we noticed a extremely skewed anti-idiotype response in all circumstances, with as much as >90% of the antibodies directed towards the idiotype. These outcomes point out that the idiotype could also be inherently immunodominant. We used these biased responses to lift monoclonal rabbit anti-idiotype antibodies in opposition to secukinumab, ustekinumab, reslizumab, mepolizumab, palivizumab, and dupilumab and display the potential to develop delicate pharmacokinetic assays with these antibodies.
Choice and Characterization of YKL-40-Concentrating on Monoclonal Antibodies from Human Artificial Fab Phage Show Libraries
YKL-40, often known as chitinase-3-like 1 (CHI3L1), is a glycoprotein that’s expressed and secreted by varied cell varieties, together with cancers and macrophages. Resulting from its implications for and upregulation in quite a lot of illnesses, together with inflammatory situations, fibrotic issues, and tumor progress, YKL-40 has been thought of as a big therapeutic biomarker. Right here, we used a phage show to develop novel monoclonal antibodies (mAbs) focusing on human YKL-40 (hYKL-40).
Human artificial antibody phage show libraries had been panned in opposition to a recombinant hYKL-40 protein, yielding seven distinctive Fabs (Antigen-binding fragment), of which two Fabs (H1 and H2) had been non-aggregating and thermally steady (75.5 °C and 76.5 °C, respectively) and had excessive obvious affinities (OkD = 2.Three nM and 4.Zero nM, respectively).
Reformatting the Fabs into IgGs (Immunoglobulin Gs) elevated their obvious affinities (notably, for H1 and H2, OkD = 0.5 nM and 0.Three nM, respectively), presumably because of the results of avidity, with little change to their non-aggregation property. The six anti-hYKL-40 IgGs had been analyzed utilizing a trans-well migration assay in vitro, revealing that three clones (H1, H2, and H4) had been notably efficient in lowering cell migration from each A549 and H460 lung most cancers cell traces.
The three clones had been additional analyzed in an in vivo animal check that assessed their anti-cancer actions, demonstrating that the tumor space and the variety of tumor nodules had been considerably decreased within the lung tissues handled with H1 (IgG). Given its excessive affinity and fascinating properties, we count on that the H1 anti-hYKL-40 mAb can be an appropriate candidate for growing anti-cancer therapeutics.
Polyclonal AntibodyP3 Polyclonal Antibody |
|||
ES6454-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against P3 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Polyclonal AntibodyP3 Polyclonal Antibody |
|||
ES6454-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against P3 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Polyclonal PML polyclonal antibody |
|||
AMR09397G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PML polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal YY1 polyclonal antibody |
|||
APR14018G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human YY1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal ETO polyclonal antibody |
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APR00372G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal SHH Polyclonal Antibody |
|||
APR00434G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SHH Polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal ETO polyclonal antibody |
|||
APR00435G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal p53 polyclonal antibody |
|||
APR00443G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal G9a polyclonal antibody |
|||
APR00448G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human G9a polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Rtf1 polyclonal antibody |
|||
APR11187G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Rtf1 polyclonal antibody |
|||
APR11188G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal SOX4 polyclonal antibody |
|||
APR13475G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SOX4 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal RARA polyclonal antibody |
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APR00370G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal EzH2 polyclonal antibody |
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APR00373G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EzH2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal BRD2 polyclonal antibody |
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APR00374G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal BMI1 polyclonal antibody |
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APR00376G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal EZH2 polyclonal antibody |
|||
APR00436G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal RARA polyclonal antibody |
|||
APR00437G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal EZH2 polyclonal antibody |
|||
APR00439G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal CHD4 polyclonal antibody |
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APR00444G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal BRD2 polyclonal antibody |
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APR00447G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Hira polyclonal antibody |
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APR00449G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Hira polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal SPI1 polyclonal antibody |
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APR00451G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SPI1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal BMI1 polyclonal antibody |
|||
APR00457G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal CHD4 polyclonal antibody |
|||
APR00459G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal MeCP2 polyclonal antibody |
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AMM06350G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal MeCP2 polyclonal antibody |
|||
AMM06351G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal PPARG polyclonal antibody |
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AMR09459G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal PPARG polyclonal antibody |
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AMR09486G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Med26 polyclonal antibody |
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APR12517G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Med26 polyclonal antibody |
|||
APR12518G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal MeCP2 polyclonal antibody |
|||
APR12525G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal MeCP2 polyclonal antibody |
|||
APR12526G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal MeCP2 polyclonal antibody |
|||
APR12527G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal PADI4 polyclonal antibody |
|||
APR08916G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PADI4 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal MYH11 polyclonal antibody |
|||
APR00438G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MYH11 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal CIITA polyclonal antibody |
|||
APR00442G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CIITA polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal HDAC1 polyclonal antibody |
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APR00445G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Spt16 polyclonal antibody |
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APR00446G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal BCL7C polyclonal antibody |
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APR00452G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BCL7C polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal LRWD1 polyclonal antibody |
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APR00455G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LRWD1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal KDM4D polyclonal antibody |
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APR00458G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human KDM4D polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal Spt16 polyclonal antibody |
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APR00460G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal ACTL6B polyclonal antibody |
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AMM05547G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTL6B polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal JARID2 polyclonal antibody |
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AMM06027G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal ZMYND8 polyclonal antibody |
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AMM08559G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZMYND8 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal JARID2 polyclonal antibody |
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APR12450G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal FKBP51 polyclonal antibody |
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APR15992G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FKBP51 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal PIWIL2 polyclonal antibody |
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APR17846G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PIWIL2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal JMJD2c polyclonal antibody |
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APR00375G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal JMJD2c polyclonal antibody |
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APR00450G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal LYDG10 polyclonal antibody |
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APR00456G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LYDG10 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal AKR1B10 Polyclonal Antibody |
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APG01659G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AKR1B10 Polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal FGF-1 Polyclonal Antibody |
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APR00423G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FGF-1 Polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal p53K372me1 polyclonal antibody |
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APR00440G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53K372me1 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal RFX-AP polyclonal antibody |
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APR00441G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RFX-AP polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal EIF2C1/2 polyclonal antibody |
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APR00453G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EIF2C1/2 polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal TGF-beta3 Polyclonal Antibody |
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APG00008G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human TGF-beta3 Polyclonal . This antibody is tested and proven to work in the following applications: |
Polyclonal sRANK Ligand Polyclonal Antibody |
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APR00294G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human sRANK Ligand Polyclonal . This antibody is tested and proven to work in the following applications: |